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Redox unbalance in the hyperthyroid cat: a comparison with healthy and non-thyroidal diseased cats.


ABSTRACT:

Background

Feline hyperthyroidism, the most common endocrinopathy in older cats, provides a spontaneous model for human thyrotoxicosis. Human thyrotoxicosis is associated with redox unbalance, which may result in organ damage. The redox status of hyperthyroid cats is largely unknown. The aims of the present study were to compare the redox status of cats with hyperthyroidism with that of healthy cats and cats with chronic non-thyroidal illness.

Results

Forty cats with untreated hyperthyroidism (group H), 45 chronically ill cats with non-thyroidal illness (group I), and 39 healthy cats (group C) were recruited for this observational cross-sectional study. All cats were screened for redox status markers. Determinable reactive oxygen metabolites (d-ROMs) were used as oxidative s

SUBMITTER: Candellone A 

PROVIDER: S-EPMC6505105 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature