Is surgical axillary staging necessary in women with T1 breast cancer who are treated with breast-conserving therapy?

ABSTRACT:

Background

In the post-Z0011 trial era, the need to perform surgical axillary staging for early-stage breast cancer patients, who are treated with breast-conserving therapy (BCT), is being questioned. We conducted a retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) database to evaluate the safety of waiving surgical axillary staging in patients with T1 breast cancer treated with BCT.

Methods

A total of 166,615 eligible patients diagnosed between 2000 and 2012 were divided into staging (sentinel lymph node biopsy or axillary lymph node dissection) and non-staging (no lymph node examined or only needle aspiration biopsy of lymph nodes) groups. Propensity score matching (PSM) was performed to balance disparities between the two groups. Mult

SUBMITTER: Wang J 

PROVIDER: S-EPMC6505128 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature