Mapping Gene Markers for Apple Fruit Ring Rot Disease Resistance Using a Multi-omics Approach.

ABSTRACT: Apple fruit ring rot (FRR), caused by Botryosphaeria dothidea, is a worldwide disease that impacts Asian apple production regions. However, no substantial progress has thus far been made toward the mapping of candidate genes or the development of effective genetic makers. In this five-year study, the resistance of 1,733 F1 hybrids from the cross 'Jonathan' × 'Golden Delicious' was phenotyped by non-wounding inoculation with four B. dothidea isolates. We first conducted systematic comparison of different analytic strategies for bulk segregant analysis by re-sequencing (BSA-Seq) and obtained suitable one for outbreeding species such as Malus Forty-six quantitative trait loci (QTL) for resistance/susceptibility to the four isolates, including one QTL 'hotspot' on chromosome 14, were identifie

SUBMITTER: Shen F 

PROVIDER: S-EPMC6505150 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature