Crystal structure of diethyl 2-amino-5-{4-[bis-(4-methyl-phen-yl)amino]-benzamido}-thio-phene-3,4-di-carboxyl-ate.

ABSTRACT: In the title compound, C31H31N3O5S, the regioselective substitution of the thio-phene is confirmed with the amine and the amide at the 2- and 5-positions, respectively. In the mol-ecule, the thio-phene ring is twisted by 12.82 (3)° with respect to the aromatic ring of the benzamido group. Intra-molecular N-H⋯O hydrogen bonds are present involving the N atoms of the primary amine and the amide groups, forming S(6) ring motifs. In the crystal, centrosymmetrically related mol-ecules are linked by pairs of N-H⋯O hydrogen bonds involving the amide carbonyl O atoms and the primary amine N atoms to form dimers of R 2 2(16) ring motif.

SUBMITTER: Gautier Y 

PROVIDER: S-EPMC6505590 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature