Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial.

ABSTRACT:

Background

Treatment decision-making regarding immunosuppressive therapy is challenging for individuals with lupus. We assessed the effectiveness of a decision aid for immunosuppressive therapy in lupus nephritis.

Methods and findings

In a United States multicenter, open-label, randomized controlled trial (RCT), adult women with lupus nephritis, mostly from racial/ethnic minority backgrounds with low socioeconomic status (SES), seen in in- or outpatient settings, were randomized to an individualized, culturally tailored, computerized decision aid versus American College of Rheumatology (ACR) lupus pamphlet (1:1 ratio), using computer-generated randomization. We hypothesized that the co-primary outcomes of decisional conflict and informed choice regarding immunosuppressive me

SUBMITTER: Singh JA 

PROVIDER: S-EPMC6505936 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature