Deficient Functioning of Frontostriatal Circuits During the Resolution of Cognitive Conflict in Cannabis-Using Youth.

ABSTRACT:

Objective

Disturbances in self-regulatory control are involved in the initiation and maintenance of addiction, including cannabis use disorder. In adults, long-term cannabis use is associated with disturbances in frontostriatal circuits during tasks that require the engagement of self-regulatory control, including the resolution of cognitive conflict. Understudied are the behavioral and neural correlates of these processes earlier in the course of cannabis use disentangled from effects of long-term use. The present study investigated the functioning of frontostriatal circuits during the resolution of cognitive conflict in cannabis-using youth.

Method

Functional magnetic resonance imaging data were acquired from 28 cannabis-using youth and 32 age-matched healthy participants

SUBMITTER: Cyr M 

PROVIDER: S-EPMC6506393 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature