Ion concentration polarization-based continuous separation device using electrical repulsion in the depletion region.

ABSTRACT: We proposed a novel separation method, which is the first report using ion concentration polarization (ICP) to separate particles continuously. We analyzed the electrical forces that cause the repulsion of particles in the depletion region formed by ICP. Using the electrical repulsion, micro- and nano-sized particles were separated based on their electrophoretic mobilities. Because the separation of particles was performed using a strong electric field in the depletion region without the use of internal electrodes, it offers the advantages of simple, low-cost device fabrication and bubble-free operation compared with conventional continuous electrophoretic separation methods, such as miniaturizing free-flow electrophoresis (μ-FFE). This separation device is expected to be a useful tool for

SUBMITTER: Jeon H 

PROVIDER: S-EPMC6506453 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature