Histologic Features Associated With an Invasive Component in Lentigo Maligna Lesions.

ABSTRACT:

Importance

Lentigo maligna (LM) presents an invasive component in up to 20% of biopsied cases, but to date the histologic features useful in detecting this invasive component have not been described. Some histologic characteristics are hypothesized to contribute to the progression of LM invasion.

Objective

To identify the histologic characteristics associated with lentigo maligna melanoma (LMM) in patients with LM diagnosed by a partial diagnostic biopsy.

Design, setting, and participants

A retrospective cross-sectional study of patients treated between January 1, 2000, and December 31, 2017, was conducted in a referral oncology center in València, Spain. Data and specimens of patients (n = 96) with a diagnosis of primary cutaneous melanoma in the form of either LM or

SUBMITTER: Moreno A 

PROVIDER: S-EPMC6506897 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature