Unraveling essential cellulosomal components of the (Pseudo)Bacteroides cellulosolvens reveals an extensive reservoir of novel catalytic enzymes.

ABSTRACT:

Background

(Pseudo)Bacteroides cellulosolvens is a cellulolytic bacterium that produces the most extensive and intricate cellulosomal system known in nature. Recently, the elaborate architecture of the B. cellulosolvens cellulosomal system was revealed from analysis of its genome sequence, and the first evidence regarding the interactions between its structural and enzymatic components were detected in vitro. Yet, the understanding of the cellulolytic potential of the bacterium in carbohydrate deconstruction is inextricably linked to its high-molecular-weight protein complexes, which are secreted from the bacterium.

Results

The current proteome-wide work reveals patterns of protein expression of the various cellulosomal components, and explores the signa

SUBMITTER: Zhivin-Nissan O 

PROVIDER: S-EPMC6507058 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature