Staphylococci phages display vast genomic diversity and evolutionary relationships.

ABSTRACT:

Background

Bacteriophages are the most abundant and diverse entities in the biosphere, and this diversity is driven by constant predator-prey evolutionary dynamics and horizontal gene transfer. Phage genome sequences are under-sampled and therefore present an untapped and uncharacterized source of genetic diversity, typically characterized by highly mosaic genomes and no universal genes. To better understand the diversity and relationships among phages infecting human pathogens, we have analysed the complete genome sequences of 205 phages of Staphylococcus sp.

Results

These are predicted to encode 20,579 proteins, which can be sorted into 2139 phamilies (phams) of related sequences; 745 of these are orphams and possess only a single gene. Based on shared gene content, these

SUBMITTER: Oliveira H 

PROVIDER: S-EPMC6507118 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature