Integrating radiosensitive genes improves prediction of radiosensitivity or radioresistance in patients with oesophageal cancer.

ABSTRACT: Oesophageal cancer is a serious disease worldwide. In China, the incidence of esophageal cancer was reported to be ~478,000 in 2015. In the same year, the incidence of esophageal cancer in the United States was ~16,910. Radiotherapy serves as an important tool in the treatment of oesophageal cancer, and although radiation therapy has progressed over time, the prognosis of the majority of patients with oesophageal cancer remains poor. Additionally, the sensitivity of patients with oesophageal cancer to radiotherapy and chemotherapy is not yet clear. Although there are a number of studies on the radiosensitivity of oesophageal cancer cell lines, the vastly different results from different cell lines make them unreliable to use as a guide in clinical practice. Therefore, a common radiosensiti

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC6507505 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature