Sero-epidemiological study in prediction of the risk groups for measles outbreaks in Vojvodina, Serbia.

ABSTRACT:

Background

Age-stratified serologic surveys provide insight into the gaps of measles-specific immunity as well as estimates of the age-specific seroprevalence. The aim of this study was to describe the measles sero-epidemiology in Vojvodina before the occurrence of outbreak in 2017/18 and to discuss preventive measures for potential future epidemics.

Methods

A seroprevalence study was conducted from April 2015 to June 2017 on serum bank of 3199 residual samples. Study was performed prior to the last measles outbreak in Vojvodina that occurred between 12th November 2017 and 30th June 2018. Measles-specific IgG antibodies were determined using an indirect chemiluminescent immunoassay (CLIA).

Results

Median age of enrolled participants was 20 years (IQR 11-37). Overall,

SUBMITTER: Ristic M 

PROVIDER: S-EPMC6508608 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature