Kcnab1 Is Expressed in Subplate Neurons With Unilateral Long-Range Inter-Areal Projections.

ABSTRACT: Subplate (SP) neurons are among the earliest-born neurons in the cerebral cortex and heterogeneous in terms of gene expression. SP neurons consist mainly of projection neurons, which begin to extend their axons to specific target areas very early during development. However, the relationships between axon projection and gene expression patterns of the SP neurons, and their remnant layer 6b (L6b) neurons, are largely unknown. In this study, we analyzed the corticocortical projections of L6b/SP neurons in the mouse cortex and searched for a marker gene expressed in L6b/SP neurons that have ipsilateral inter-areal projections. Retrograde tracing experiments demonstrated that L6b/SP neurons in the primary somatosensory cortex (S1) projected to the primary motor cortex (M1) within the same cort

SUBMITTER: Tiong SYX 

PROVIDER: S-EPMC6509479 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature