DiVenn: An Interactive and Integrated Web-Based Visualization Tool for Comparing Gene Lists.

ABSTRACT: Gene expression data generated from multiple biological samples (mutant, double mutant, and wild-type) are often compared via Venn diagram tools. It is of great interest to know the expression pattern between overlapping genes and their associated gene pathways or gene ontology (GO) terms. We developed DiVenn (Dive into the Venn diagram and create a force directed graph)-a novel web-based tool that compares gene lists from multiple RNA-Seq experiments in a force-directed graph, which shows the gene regulation levels for each gene and integrated KEGG pathway and gene ontology knowledge for the data visualization. DiVenn has four key features: (1) informative force-directed graph with gene expression levels to compare multiple data sets; (2) interactive visualization with biological annotati

SUBMITTER: Sun L 

PROVIDER: S-EPMC6509638 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature