Comparative analyses of the variation of the transcriptome and proteome of Rhodobacter sphaeroides throughout growth.

ABSTRACT:

Background

In natural environments, bacteria must frequently cope with extremely scarce nutrients. Most studies focus on bacterial growth in nutrient replete conditions, while less is known about the stationary phase. Here, we are interested in global gene expression throughout all growth phases, including the adjustment to deep stationary phase.

Results

We monitored both the transcriptome and the proteome in cultures of the alphaproteobacterium Rhodobacter sphaeroides, beginning with the transition to stationary phase and at different points of the stationary phase and finally during exit from stationary phase (outgrowth) following dilution with fresh medium. Correlation between the transcriptomic and proteomic changes was very low throughout the growth phases. Surprisingly

SUBMITTER: Bathke J 

PROVIDER: S-EPMC6509803 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature