Potential biological therapies for severe preeclampsia: a systematic review and meta-analysis.

ABSTRACT:

Background

Preeclampsia remains a significant danger to both mother and child and current prevention and treatment management strategies are limited. The objective of this systematic review was to investigate the current literature on evidence for the use of the regenerative capacity of mesenchymal stem cell (MSC) therapy, the anticoagulant activity of antithrombin (AT), or the free radical scavenging activity of alpha-1-microglobulin (A1M) as potential novel treatments for severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelet count (HELLP).

Method

We conducted a systematic review of potential biological therapies for preeclampsia. We screened MEDLINE and Embase from inception through May 2017 for studies using AT, A1M or MSCs as potential treatments for pr

SUBMITTER: Grimes S 

PROVIDER: S-EPMC6509856 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature