Genomic Evaluation for a Crossbreeding System Implementing Breed-of-Origin for Targeted Markers.

ABSTRACT: The genome in crossbred animals is a mosaic of genomic regions inherited from the different parental breeds. We previously showed that effects of haplotypes strongly associated with crossbred performance are different depending upon from which parental breed they are inherited, however, the majority of the genomic regions are not or only weakly associated with crossbred performance. Therefore, our objective was to develop a model that distinguishes between selected single nucleotide polymorphisms (SNP) strongly associated with crossbred performance and all remaining SNP. For the selected SNP, breed-specific allele effects were fitted whereas for the remaining SNP it was assumed that effects are the same across breeds (SEL-BOA model). We used data from three purebred populations; S, LR, and

SUBMITTER: Sevillano CA 

PROVIDER: S-EPMC6510010 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature