Endocrine Therapy Nonadherence and Discontinuation in Black and White Women.

ABSTRACT:

Background

Differential use of endocrine therapy (ET) by race may contribute to breast cancer outcome disparities, but racial differences in ET behaviors are poorly understood.

Methods

Women aged 20-74 years with a first primary, stage I-III, hormone receptor-positive (HR+) breast cancer were included. At 2 years postdiagnosis, we assessed nonadherence, defined as not taking ET every day or missing more than two pills in the past 14 days, discontinuation, and a composite measure of underuse, defined as either missing pills or discontinuing completely. Using logistic regression, we evaluated the relationship between race and nonadherence, discontinuation, and overall underuse in unadjusted, clinically adjusted, and socioeconomically adjusted models.

Results

A total of

SUBMITTER: Wheeler SB 

PROVIDER: S-EPMC6510227 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature