Robust CT ventilation from the integral formulation of the Jacobian.

ABSTRACT: Computed tomography (CT) derived ventilation algorithms estimate the apparent voxel volume changes within an inhale/exhale CT image pair. Transformation-based methods compute these estimates solely from the spatial transformation acquired by applying a deformable image registration (DIR) algorithm to the image pair. However, approaches based on finite difference approximations of the transformation's Jacobian have been shown to be numerically unstable. As a result, transformation-based CT ventilation is poorly reproducible with respect to both DIR algorithm and CT acquisition method.

Purpose

We introduce a novel Integrated Jacobian Formulation (IJF) method for estimating voxel volume changes under a DIR-recovered spatial transformation. The method is based on computing volume estima

SUBMITTER: Castillo E 

PROVIDER: S-EPMC6510605 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature