Impact of medical therapy for cardiovascular disease on left ventricular diastolic properties and remodeling.

ABSTRACT:

Background

Left ventricular (LV) remodeling and diastolic properties are affected by both underlying cardiovascular disease/cardiovascular disease risk factors (CVDRFs) and corresponding medication therapy. However, these effects may not be apparent in patients with multiple CVDRFs. We evaluated the effect of medication classes on hemodynamics in a patient cohort with normal LV dimensions and systolic function.

Methods

In 38 participants (61 ± 7 years, 64 ± 9% LV ejection fraction) undergoing coronary angiography, LV pressure measurement and cardiac magnetic resonance imaging was performed. The effects of coronary artery disease (CAD), CVDRFs and their corresponding medication therapy on LV parameters were analyzed considering the number of CAD/CVDRFs and 'adequacy' of medic

SUBMITTER: Sharifov OF 

PROVIDER: S-EPMC6510698 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature