Localization yield and seizure outcome in patients undergoing bilateral SEEG exploration.

ABSTRACT:

Objective

We aimed to determine the rates and predictors of resection and seizure freedom after bilateral stereo-electroencephalography (SEEG) implantation.

Methods

We reviewed 184 patients who underwent bilateral SEEG implantation (2009-2015). Noninvasive and invasive evaluation findings were collected. Outcomes of interest included subsequent resection and seizure freedom. Statistical analyses employed multivariable logistic regression and proportional hazard modeling. Preoperative and postoperative seizure frequency, severity, and quality of life scales were also compared.

Results

Following bilateral SEEG implantation, 106 of 184 patients (58%) underwent resection. Single seizure type (P = 0.007), a family history of epilepsy (P = 0.003), 10 or more seizures per mo

SUBMITTER: Steriade C 

PROVIDER: S-EPMC6510950 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature