Comparing signals of natural selection between three Indigenous North American populations.

ABSTRACT: While many studies have highlighted human adaptations to diverse environments worldwide, genomic studies of natural selection in Indigenous populations in the Americas have been absent from this literature until very recently. Since humans first entered the Americas some 20,000 years ago, they have settled in many new environments across the continent. This diversity of environments has placed variable selective pressures on the populations living in each region, but the effects of these pressures have not been extensively studied to date. To help fill this gap, we collected genome-wide data from three Indigenous North American populations from different geographic regions of the continent (Alaska, southeastern United States, and central Mexico). We identified signals of natural selection

SUBMITTER: Reynolds AW 

PROVIDER: S-EPMC6511053 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature