Longitudinal brain morphology in anti-NMDA receptor encephalitis: a case report with controls.

ABSTRACT:

Background

Anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis is a severe autoimmune condition, which typically affects young females. The long-term clinical consequences and brain morphology changes after anti-NMDAR encephalitis are not well known.

Case presentation

We present clinical and neuroimaging follow-up data on a 25-year female patient with typically presenting anti-NMDAR encephalitis. Longitudinal analyses of brain morphology were done using 3 T structural magnetic resonance imaging (sMRI) and Freesurfer analysis at the time of diagnosis and after symptomatic remission. The presented case attained good functional recovery after standard immunoglobulin-corticosteroid treatment but elevated serum NMDAR antibody levels persisted. The patient had no symptomatic r

SUBMITTER: Laurikainen H 

PROVIDER: S-EPMC6511133 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature