Outcomes of nonmetastatic micropapillary variant upper tract urothelial carcinoma.

ABSTRACT:

Purpose

Micropapillary variant upper tract urothelial cancer (MP-UTUC) is a rare malignancy with little known regarding its clinical course and/or optimal treatment. In this case series, we describe patient characteristics, surgical treatment, oncologic outcomes, and response to perioperative chemotherapy.

Materials and methods

We conducted a review to identify patients with MP-UTUC treated at our center between January 1994 and October 2017. Clinicopathologic data was obtained. Descriptive statistics, Kaplan-Meier analysis, Cox proportional hazards, and nearest neighbor matching were used to examine the cohort.

Results

Eighteen, (4.3%) of 416 patients were found to have MP-UTUC at our institution over a 23-year period. The majority of patients had ≥pT3 disease at the

SUBMITTER: Duplisea JJ 

PROVIDER: S-EPMC6511295 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature