Gene Structure and Sequence Polymorphism of the Coat Color Gene, Mc1r, in the Black-Bellied Vole (Eothenomys melanogaster).

ABSTRACT: Yung-Chih Lai, Shiao-Wei Huang, and Hon-Tsen Yu (2016) Color polymorphism is a long-standing issue in ecological and evolutionary biology. The black-bellied vole (Eothenomys melanogaster) with complete melanic and brown forms provides an outstanding opportunity to study the genetic polymorphism underpinning color variation. Mutations in the coding region of melanocortin 1 receptor (Mc1r) have been shown to cause color variation in a wide range of species. However, the contribution to color variation produced by the Mc1r regulatory regions have rarely been studied in wild animals. To this end, the Mc1r promoter sequence in black-bellied voles was cloned and characterized in this study. At least 11 distinct transcription initiation sites were identified usi

SUBMITTER: Lai YC 

PROVIDER: S-EPMC6511826 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature