Prenatal, intrapartum, and postnatal factors are associated with pediatric eosinophilic esophagitis.

ABSTRACT:

Background

Multiple lines of evidence point to the potential importance of early-life environmental factors in the rapid increase in the incidence of eosinophilic esophagitis (EoE), but potential exposures have not been extensively studied.

Objective

We sought to assess the association between prenatal, intrapartum, and postnatal factors and the development of pediatric EoE using a case-control study.

Methods

Patients with EoE were recruited from an existing registry at Cincinnati Children's Hospital Medical Center (CCHMC). Population-based community control subjects were identified from a separate CCHMC registry. Mothers of study subjects were contacted and completed a Web-based questionnaire. Crude and adjusted models were used to estimate associations.

Results</

SUBMITTER: Jensen ET 

PROVIDER: S-EPMC6511884 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature