Tolerability and blinding of 4x1 high-definition transcranial direct current stimulation (HD-tDCS) at two and three milliamps.

ABSTRACT:

Background

Transcranial direct current stimulation (tDCS) is an in-demand form of neuromodulation generally regarded as safe and well tolerated. However, few studies have examined the safety, tolerability, or blinding of High Definition (HD-) tDCS, especially in older adults and at stimulation intensities of 2 milliamps (mA) or greater.

Objective

We examined the rates of serious adverse events and common side effects to establish safety and tolerability, respectively, in HD-tDCS. Blinding was evaluated using participants' accuracy in correctly stating their condition (i.e., active or sham).

Methods

The sample included 101 older adults (M_age = 69.69, SD = 8.33; M_educ = 16.27, SD = 2.42) who participated in our double blind randomized controlled st

SUBMITTER: Reckow J 

PROVIDER: S-EPMC6512313 | biostudies-literature | 2018 Sep - Oct

REPOSITORIES: biostudies-literature