Diagnosis validation and clinical characterization of atopic dermatitis in Nurses' Health Study 2.

ABSTRACT:

Background

Epidemiologic studies of atopic dermatitis (AD) are often limited by case definitions that have not been validated.

Objective

In this study, we assessed the accuracy of self-report of AD in a large cohort of US female nurses, the Nurses' Health Study 2 (NHS2). We also provide clinical characteristics of AD in the cohort.

Methods

We sent an electronic questionnaire to NHS2 participants who previously reported ever having a diagnosis of AD. This questionnaire was designed to confirm cases of AD using previously validated algorithms with >85% specificity. We assessed the association of AD with asthma, comparing the results when different definitions of AD were applied. We also inquired about various aspects of participants' AD.

Results

Responses were re

SUBMITTER: Drucker AM 

PROVIDER: S-EPMC6512329 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature