A core set of venom proteins is released by entomopathogenic nematodes in the genus Steinernema.

ABSTRACT: Parasitic helminths release molecular effectors into their hosts and these effectors can directly damage host tissue and modulate host immunity. Excreted/secreted proteins (ESPs) are one category of parasite molecular effectors that are critical to their success within the host. However, most studies of nematode ESPs rely on in vitro stimulation or culture conditions to collect the ESPs, operating under the assumption that in vitro conditions mimic actual in vivo infection. This assumption is rarely if ever validated. Entomopathogenic nematodes (EPNs) are lethal parasites of insects that produce and release toxins into their insect hosts and are a powerful model parasite system. We compared transcriptional profiles of individual Steinernema feltiae nematodes at different time points of act

SUBMITTER: Chang DZ 

PROVIDER: S-EPMC6513111 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature