ParGenes: a tool for massively parallel model selection and phylogenetic tree inference on thousands of genes.

ABSTRACT:

Motivation

Coalescent- and reconciliation-based methods are now widely used to infer species phylogenies from genomic data. They typically use per-gene phylogenies as input, which requires conducting multiple individual tree inferences on a large set of multiple sequence alignments (MSAs). At present, no easy-to-use parallel tool for this task exists. Ad hoc scripts for this purpose do not only induce additional implementation overhead, but can also lead to poor resource utilization and long times-to-solution. We present ParGenes, a tool for simultaneously determining the best-fit model and inferring maximum likelihood (ML) phylogenies on thousands of independent MSAs using supercomputers.

Results

ParGenes executes common phylogenetic pipeline steps such as model-testing, ML

SUBMITTER: Morel B 

PROVIDER: S-EPMC6513153 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature