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Antipsychotics for treatment of delirium in hospitalised non-ICU patients.


ABSTRACT:

SUBMITTER: Burry L 

PROVIDER: S-EPMC6513380 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Antipsychotics for treatment of delirium in hospitalised non-ICU patients.

Burry Lisa L   Mehta Sangeeta S   Perreault Marc M MM   Luxenberg Jay S JS   Siddiqi Najma N   Hutton Brian B   Fergusson Dean A DA   Bell Chaim C   Rose Louise L  

The Cochrane database of systematic reviews 20180618


<h4>Background</h4>Guidelines suggest limited and cautious use of antipsychotics for treatment of delirium where nonpharmacological interventions have failed and symptoms remain distressing or dangerous, or both. It is unclear how well these recommendations are supported by current evidence.<h4>Objectives</h4>Our primary objective was to assess the efficacy of antipsychotics versus nonantipsychotics or placebo on the duration of delirium in hospitalised adults. Our secondary objectives were to c  ...[more]

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