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Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia.

ABSTRACT:

SUBMITTER: Sadaf A

PROVIDER: S-EPMC6513605 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia.

Sadaf Alina A Hasan Babar B Das Jai K JK Colan Steven S Alvi Najveen N

The Cochrane database of systematic reviews 20180712

<h4>Background</h4>Beta thalassaemia is a common inherited blood disorder. The need for frequent blood transfusions in this condition poses a difficult problem to healthcare systems. The most common cause of morbidity and mortality is cardiac dysfunction from iron overload. The use of iron chelation therapy has reduced the severity of systemic iron overload but specific, non-toxic treatment is required for removal of iron from the myocardium.<h4>Objectives</h4>To assess the effects of calcium ch ...[more]

PMID: 29998494

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