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Theaflavin-Enriched Fraction Stimulates Adipogenesis in Human Subcutaneous Fat Cells.


ABSTRACT: Skin provides the first defense line against the environment while preserving physiological homeostasis. Subcutaneous tissues including fat depots that are important for maintaining skin structure and alleviating senescence are altered during aging. This study investigated whether theaflavin (TF) in green tea (GT) has skin rejuvenation effects. Specifically, we examined whether high ratio of TF contents can induce the subcutaneous adipogenesis supporting skin structure by modulating lipid metabolism. The co-fermented GT (CoF-GT) fraction containing a high level of TF was obtained by co-fermentation with garland chrysanthemum (Chrysanthemum coronarium) and the conventionally fermented GT (F-GT) fraction was also obtained. The effects of the CoF- or F-GT fractions on adipogenesis were

SUBMITTER: Park PJ 

PROVIDER: S-EPMC6515531 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature