Vasopressors for hypotensive shock.

ABSTRACT:

Background

Initial goal-directed resuscitation for hypotensive shock usually includes administration of intravenous fluids, followed by initiation of vasopressors. Despite obvious immediate effects of vasopressors on haemodynamics, their effect on patient-relevant outcomes remains controversial. This review was published originally in 2004 and was updated in 2011 and again in 2016.

Objectives

Our objective was to compare the effect of one vasopressor regimen (vasopressor alone, or in combination) versus another vasopressor regimen on mortality in critically ill participants with shock. We further aimed to investigate effects on other patient-relevant outcomes and to assess the influence of bias on the robustness of our effect estimates.

Search methods

We searched the

SUBMITTER: Gamper G 

PROVIDER: S-EPMC6516856 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature