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Cannabis for the treatment of Crohn's disease.


ABSTRACT:

SUBMITTER: Kafil TS 

PROVIDER: S-EPMC6517156 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Cannabis for the treatment of Crohn's disease.

Kafil Tahir S TS   Nguyen Tran M TM   MacDonald John K JK   Chande Nilesh N  

The Cochrane database of systematic reviews 20181108


<h4>Background</h4>Crohn's disease (CD) is a chronic immune-mediated condition of transmural inflammation in the gastrointestinal tract, associated with significant morbidity and decreased quality of life. The endocannabinoid system provides a potential therapeutic target for cannabis and cannabinoids and animal models have shown benefit in decreasing inflammation. However, there is also evidence to suggest transient adverse events such as weakness, dizziness and diarrhea, and an increased risk  ...[more]

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