Triple and quadruple cervical artery dissections: a systematic review of individual patient data.

ABSTRACT:

Background and purpose

Simultaneous dissection of three or four cervical arteries rarely occurs. As a result, limited information is available on clinical characteristics, underlying causes, treatment, and outcome of these patients.

Methods

We performed a systematic review of individual patient data on triple and quadruple cervical artery dissection (CeAD). We included all cases for whom, at minimum, data on age, sex and affected cervical arteries were available.

Results

Out of 1396 publications identified in the initial search, 52 were included, with data available on 96 patients. Mean age was 42 years and 66% were women. 63% had triple CeAD. The most common manifestations were headache (69%), neck pain (44%), motor deficit (36%), and Horner syndrome (34%). 57% had a

SUBMITTER: Guglielmi V 

PROVIDER: S-EPMC6517349 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature