Reduced Upper Limb Recovery in Subcortical Stroke Patients With Small Prior Radiographic Stroke.

ABSTRACT: Background: Research imaging costs limit lesion-based analyses in already expensive large stroke rehabilitation trials. Despite the belief that lesion characteristics influence recovery and treatment response, prior studies have not sufficiently addressed whether lesion features are an important consideration in motor rehabilitation trial design. Objective: Using clinically-obtained neuroimaging, evaluate how lesion characteristics relate to upper extremity (UE) recovery and response to therapy in a large UE rehabilitation trial. Methods: We reviewed lesions from 297 participants with mild-moderate motor impairment in the Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (ICARE) study and their association with motor recovery, measured by the UE Fugl-Meyer

SUBMITTER: Edwardson MA 

PROVIDER: S-EPMC6517555 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature