Endocannabinoid Metabolome Characterization of Milk from Guatemalan Women Living in the Western Highlands.

ABSTRACT:

Background

Recognized as the gold-standard ideal fare, human milk has a unique composition that meets infants' needs throughout development. Endocannabinoids and endocannabinoid-like compounds [endocannabinoid metabolome (ECM)] are endogenous lipid mediators derived from long-chain polyunsaturated fatty acids. Based on animal models, it has been proposed that endocannabinoid arachidonoyl glycerol (AG) plays a role in establishing the suckling response during lactation. In addition, endocannabinoid ethanolamides have been shown to stimulate food intake. The mechanisms of action and the role of the ECM in human milk are not fully understood.

Objectives

The present study aimed to characterize and quantify the ECM in human milk samples from an underserved population in Guatemala

SUBMITTER: Gaitan AV 

PROVIDER: S-EPMC6517780 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature