Clinicopathologic predictors of metastasis of different regional lymph nodes in patients intraoperatively diagnosed with stage-I non-small cell lung cancer.

ABSTRACT:

Background

Selection of the best lymph node for dissection is a controversial topic in clinical stage-I non-small cell lung cancer (NSCLC). Here, we sought to identify the clinicopathologic predictors of regional lymph node metastasis in patients intraoperatively diagnosed with stage-I NSCLC.

Methods

A retrospective review of 595 patients intraoperatively diagnosed as stage I non-small-cell lung cancer who underwent lobectomy with complete lymph node dissection was performed. Univariate and multivariable logistic regression analysis was performed to determine the independent predictors of regional lymph node metastasis.

Results

Univariate logistic regression and multivariable analysis revealed three independent predictors of the presence of metastatic hilar lymph node

SUBMITTER: Zhao F 

PROVIDER: S-EPMC6518627 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature