Fractional exhaled nitric oxide in preterm-born subjects: A systematic review and meta-analysis.

ABSTRACT:

Background

Decreased lung function is common in preterm-born survivors. Increased fractional exhaled nitric oxide (FeNO) appears to be a reliable test for eosinophillic airway inflammation especially in asthma. We, systematically, reviewed the literature to compare FeNO levels in preterm-born children and adults who did or did not have chronic lung disease of prematurity (CLD) in infancy with term-born controls.

Methods

We searched eight databases up to February 2018. Studies comparing FeNO levels in preterm-born subjects (<37 weeks' gestation) in childhood and adulthood with and without (CLD) with term-born subjects were identified and extracted by two reviewers. Data were analysed using Review Manager v5.3.

Results

From 6042 article titles, 183 full articles were sc

SUBMITTER: Course CW 

PROVIDER: S-EPMC6519366 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature