Evidence-Based Applications of Combination Psychotherapy and Pharmacotherapy for Depression.

ABSTRACT: Combination treatment with psychotherapy and antidepressant medication can be provided from the initiation of treatment, sequentially after nonremission with a single-modality treatment or sequentially after remission to buttress the patient's recovery to prevent recurrence. Combination treatment from the initiation of care is best reserved for patients with high depression severity. Sequential addition of treatments, particularly psychotherapy after nonremission to antidepressant medication, is the best supported method of combination, improving remission rates and reducing relapse and recurrence in the long term. However, uncertainty persists around the optimal form of psychotherapy to combine with antidepressant medication for maximizing long-term gains. Better outcomes from combination

SUBMITTER: Dunlop BW 

PROVIDER: S-EPMC6519650 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature