A Systematic Risk Assessment and Meta-Analysis on the Use of Oral β-Alanine Supplementation.

ABSTRACT: β-Alanine supplementation is one of the world's most commonly used sports supplements, and its use as a nutritional strategy in other populations is ever-increasing, due to evidence of pleiotropic ergogenic and therapeutic benefits. Despite its widespread use, there is only limited understanding of potential adverse effects. To address this, a systematic risk assessment and meta-analysis was undertaken. Four databases were searched using keywords and Medical Subject Headings. All human and animal studies that investigated an isolated, oral, β-alanine supplementation strategy were included. Data were extracted according to 5 main outcomes, including 1) side effects reported during longitudinal trials, 2) side effects reported during acute trials, 3) effect of supplementation on circulating

SUBMITTER: Dolan E 

PROVIDER: S-EPMC6520041 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature