Computed tomography porosity and spherical indentation for determining cortical bone millimetre-scale mechanical properties.

ABSTRACT: The cortex of the femoral neck is a key structural element of the human body, yet there is not a reliable metric for predicting the mechanical properties of the bone in this critical region. This study explored the use of a range of non-destructive metrics to measure femoral neck cortical bone stiffness at the millimetre length scale. A range of testing methods and imaging techniques were assessed for their ability to measure or predict the mechanical properties of cortical bone samples obtained from the femoral neck of hip replacement patients. Techniques that can potentially be applied in vivo to measure bone stiffness, including computed tomography (CT), bulk wave ultrasound (BWUS) and indentation, were compared against in vitro techniques, including compression testing, density measure

SUBMITTER: Boughton OR 

PROVIDER: S-EPMC6520408 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature