Longitudinal effects of race, ethnicity, and psychosocial disadvantage on systemic inflammation.

ABSTRACT:

Objective

Psychosocial factors likely contribute to racial and ethnic inequalities in cardiovascular diseases (CVDs). However, precise social, psychological, and physiological pathways linking race and ethnicity to the development of CVDs are not well understood. Systemic inflammation, commonly indexed by C-reactive protein (CRP), is a biomarker for CVD risk and progression. The objective of this study was to identify mediating pathways from race and ethnicity to CRP through social, psychological, and behavioral variables.

Methods

Using data from 12,382 participants aged 51 and older in the Health and Retirement Study, structural equation models tested for direct and indirect effects of race and ethnicity on CRP measured over four years through educational disadvantage, ever

SUBMITTER: Zahodne LB 

PROVIDER: S-EPMC6520605 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature