Association between Dietary Cholesterol and Their Food Sources and Risk for Hypercholesterolemia: The 2012⁻2016 Korea National Health and Nutrition Examination Survey.

ABSTRACT: It remains unclear whether cholesterol intake can increase serum cholesterol. Therefore, the present study aimed to investigate the hypothesis that the risk for hypercholesterolemia was not associated with intake of dietary cholesterol after adjusting for saturated fatty acid (SFA). Based on the data from the 2012-2016 KNHANES, dietary cholesterol was positively associated with the risk for abnormalities in total cholesterol (TC) (odds ratio (OR): 1.153, 95% confidence interval (CI): 0.995-1.337; p = 0.028) and low-density lipoprotein cholesterol (LDL-C) (OR: 1.186, 95% CI: 1.019-1.382; p = 0.018) levels before adjusting for SFA; after adjusting for SFA, no significant associations were found between these variables. The mediation analysis showed that dietary cholesterol had no direct effe

SUBMITTER: Cha D 

PROVIDER: S-EPMC6520795 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature