Enzymatic and molecular characterization of insecticide resistance mechanisms in field populations of Aedes aegypti from Selangor, Malaysia.

ABSTRACT:

Background

Dengue is a serious public health problem worldwide, including in Selangor, Malaysia. Being an important vector of dengue virus, Aedes aegypti are subjected to control measures which rely heavily on the usage of insecticides. Evidently, insecticide resistance in Ae. aegypti, which arise from several different point mutations within the voltage-gated sodium channel genes, has been documented in many countries. Thus, this robust study was conducted in all nine districts of Selangor to understand the mechanisms of resistance to various insecticides in Ae. aegypti. Mosquitoes were collected from dengue epidemic and non-dengue outbreak areas in Selangor.

Methods

Using the Center for Disease Control and Prevention (CDC) bottle assays, the insecticide resistance status o

SUBMITTER: Leong CS 

PROVIDER: S-EPMC6521414 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature