Early-life home environment and risk of asthma among inner-city children.

ABSTRACT:

Background

Environmental exposures in early life appear to play an important role in the pathogenesis of childhood asthma, but the potentially modifiable exposures that lead to asthma remain uncertain.

Objective

We sought to identify early-life environmental risk factors for childhood asthma in a birth cohort of high-risk inner-city children.

Methods

We examined the relationship of prenatal and early-life environmental factors to the occurrence of asthma at 7 years of age among 442 children.

Results

Higher house dust concentrations of cockroach, mouse, and cat allergens in the first 3 years of life were associated with lower risk of asthma (for cockroach allergen: odds ratio per interquartile range increase in concentration, 0.55; 95% CI, 0.36-0.86; P < .01). H

SUBMITTER: O'Connor GT 

PROVIDER: S-EPMC6521865 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature