Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration.

ABSTRACT: To evaluate whether occupational attainment influences the trajectory of longitudinal cognitive decline in behavioral variant frontotemporal degeneration (bvFTD). Single-center, retrospective, longitudinal study. Sixty-three patients meeting consensus criteria for bvFTD underwent evaluation at the University of Pennsylvania Frontotemporal Degeneration Center. All patients were studied longitudinally on letter-guided fluency, category-naming fluency and Boston Naming Test (BNT). Occupational attainment was defined categorically by assigning each individual's occupation to a professional or non-professional category. Linear mixed-effects models evaluated the interaction of neuropsychological performance change with occupational status. Regression analyses were used to relate longitudinal dec

SUBMITTER: Massimo L 

PROVIDER: S-EPMC6521965 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature