A breast cancer case-control study of polybrominated diphenyl ether (PBDE) serum levels among California women.

ABSTRACT:

Purpose

Polybrominated diphenyl ethers (PBDEs) are among the most persistent and pervasive global environmental contaminants. Their toxic and endocrine-disrupting properties have made them a focus of concern for breast cancer. Our objective was to evaluate the risk of breast cancer associated with serum PBDE levels in a case-control study nested within the California Teachers Study.

Methods

Participants were 902 women with invasive breast cancer (cases) and 936 with no such diagnosis (controls) who provided 10 mL of blood and were interviewed between 2011 and 2015. Blood samples were collected from cases an average of 35 months after diagnosis. PBDEs were measured in serum using automated solid phase extraction and gas chromatography/high resolution mass spectrometry. Statis

SUBMITTER: Hurley S 

PROVIDER: S-EPMC6522143 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature