Electrospin-Coating of Paper: A Natural Extracellular Matrix Inspired Design of Scaffold.

ABSTRACT: Paper has recently found widespread applications in biomedical fields, especially as an alternative scaffolding material for cell cultures, owing to properties such as its fibrous nature, porosity and flexibility. However, paper on its own is not an optimal material for cell cultures as it lacks adhesion moieties specific to mammalian cells, and modifications such as hydrogel integration and chemical vapor deposition are necessary to make it a favorable scaffolding material. The present study focuses on modification of filter paper through electrospin-coating and dip-coating with polycaprolactone (PCL), a promising biomaterial in tissue engineering. Morphological analysis, evaluation of cell viability, alkaline phosphatase (ALP) activity and live/dead assays were conducted to study the pot

SUBMITTER: Ng K 

PROVIDER: S-EPMC6523310 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature